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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinopathy of prematurity (ROP)
ncRNA name Robo1 siRNA
ncRNA Category siRNA
Disease name retinopathy of prematurity (ROP)
Species Macaca mulatta
Tissues/Cell_line rhesus choroid-retinal endothelial cell line RF/6A
Methods siRNA transfection, immunocytochemistry, MTT assay, cell attachment assay, migration assay, flow cytometry, tube formation assay
Expression pattern associated
Functional description Robo1 expression was elevated in the ROP murine eyes (P < 0.01). Knockdown of Robo1 expression inhibited cell proliferation and migration. Tube formation by RF/6A was also disturbed.
PubMed ID 19958120
Year 2009
Title Robo1: a potential role in ocular angiogenesis.
Drug-related ncRNA NO

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